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<br>Background: Intradialytic hypotension (IDH) has a dramatic impression on the principle outcomes of dialysis patients. Early warning of hemodynamic worsening during dialysis would allow preventive measures to be taken. Blood oxygen saturation (SO2) is used for hemodynamic monitoring within the critical care setting and will present helpful details about IDH onset. Aim: To evaluate whether brief- and medium-time period variations in the SO2 signal (ST-SO2var, MT-SO2var,) during dialysis are a predictor of IDH. Methods: On this 3-month observational cohort study, fifty one hypotension-prone chronic hemodialysis (HD) patients, with vascular entry by arteriovenous fistula (AVF) or central venous catheter (CVC), were enrolled. 0.2 Hz) by an optical sensor on the arterial line of the extracorporeal circulation |